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Hello, and welcome to module two.

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Well, now we're gonna jump
right on into the material,

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the heart of the foundation
of genetics and genomics.

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So we're going to take it
from the first lecture,

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the cell perspective, and just
break it down to, you know,

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where is DNA, how is it
existing in the cell?

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How is it affecting, why does it matter?

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How does it affect how
tissues and cells function?

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So we're gonna take a look there,

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and then we're gonna move
to the second lecture

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in the module on DNA structure.

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Now, I know structure in biochemistry

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can sometimes elicit
really painful memories,

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and believe me, I understand that.

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When I go through structure,

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I'm really just going to focus on

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what I think is necessary

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and important for you to have
a sufficient understanding

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to move forward with
what we're going to learn

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in the rest of the course.

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It's not going to be
every last little atom

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and hydrogen bond and all of that.

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It's really just, here
are the fundamentals.

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Here's what you need to understand,
so that then we can take

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that understanding
forward to the next module

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and build on it from there,

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and then take it out more broadly to

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a clinical understanding
of what's going on.

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So, worry not.

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Hopefully, I have been able
to really just focus in

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on the parts that are going
to be necessary for you.

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And then the third lecture is going to be

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on the central dogma,

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which I know sounds like I'm starting

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to teach you philosophy,

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but actually is, is a really critical,

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as you can tell from the name,

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really critical concept in genetics

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and really all of biology.

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And it's going to be one
that's absolutely critical

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for us to understand before we move on.

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So for some of you who maybe
have had genetics classes

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in the past or more bio
classes in the past,

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this is probably going
to be a review for you,

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and I think that's great.

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You know, hopefully
you'll at least, you know,

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fire up those neurons again,

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that hold the memories of
all of this kind of material.

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For those of you who are
new to this or, you know,

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it's been a while since
you covered this material,

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the goal here is really
to set the foundation

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and set one that we're all on an even,

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on an even playing field
when we move on from here.

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So even if it's a review for you,

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hopefully you get something new out of it,

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or at least a good refresher on it.

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If it is new to you,

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my goal again is to provide
you sufficient amount of

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information and perspective
to, to give you the,

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a solid base for us to
really build from there.

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So, as with all modules, you're
going to have your lectures,

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and I have a voiceover
PowerPoint for those

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in the lectures folder, as
well as the PowerPoint files

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that go along with those if you'd like to,

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to have those to take notes on.

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Then we have a quiz that
you can, again, as always,

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take up to three times with
your highest score recorded

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and a discussion board post here.

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I have a prompt for you that
I'd like you to respond to.

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And then I also have another
forum that I've set up

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for module two, which was
just any kind of questions

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that you might have or
comments that you want to make

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that's not related to the
specific prompts I'm giving you

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for this week.

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I want you to have a space
to be able to, you know,

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to bring those questions
up or make those comments

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and, you know, have some
discussion going there as well.

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So that's available.

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The assignment for this week is, again,

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since this is really,

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really the fundamentals of genetics,

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I want to make sure we're
all on the same page

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with the vocabulary that we're using.

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So I have a list of terms
that are critical terms for,

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for genetics, and I'd
like you to define those.

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So it's a Word document,
you just download it

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and then you can type
in for each of the terms

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that I have there in the definition.

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And I'd encourage you to try to do this

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after you've gone through
the lecture material,

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after you've done the
reading that you can go back

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and then see if maybe
there's some terms that

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you thought you knew, but
then when you actually put,

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started to write it out you realize

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maybe I don't quite fully understand that.

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That'll be a helpful cue to you to know

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where maybe you can go back
and look at that section again

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a little more closely.

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So maybe just try it
the first time through

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without using your books and notes

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and then see where you're
having a little bit

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of a struggle to define it,

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and then go back and look that up again.

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So the assignment is there.

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The required reading,
you have just a few pages

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from the textbook this week

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because I want to make sure
again that we're getting those,

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the fundamentals down and not
much in the textbook on that.

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So I have that.

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But then to supplement it,

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because the textbook doesn't
have a ton of information on

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some of these basic concepts,

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I've included some excerpts
from a book chapter that I wrote

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on genetics and it covers
all of these terms as well.

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So that can be another
resource for you to use.

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And in that textbook chapter,

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I have some practice questions

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and things like that with
answers posted at the end

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if you're, if you're
interested in doing that.

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But just to give you
another resource to use to

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better understand some of these concepts.

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Alright, well, I believe that
will cover it for this week.

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It was so great to read
all of your introductions.

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Thank you all for introducing yourselves.

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I'm really excited.

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This is such a wonderful group of,

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of folks on board for
this, for this semester,

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and I really look forward
to engaging with each of you

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and bringing in your
individual backgrounds

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and experiences to the course.

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And we already had some
great questions coming up

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and some discussions based upon those,

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and I look forward to keeping that up.

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And yeah so with that, I
will close out for this week.

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Just want to say if this is
kind of like your first foray

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back into molecular biology or genetics,

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I understand, believe me,

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I understand this can seem a
bit overwhelming when you start

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jumping back into this kind of material.

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It's a way of thinking
that maybe you haven't

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engaged in in a while

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or wasn't something that
you really focused on

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when you were in college.

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I totally understand that.

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It can seem, you know, a bit foreign,

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like a totally different
language and you know,

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you're jumping into it.

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But I think actually the
foreign language analogy's

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a good one.

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When you start learning
a foreign language,

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it all sounds foreign, right?

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It all sounds overwhelming

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and tough to know how to even
jump in there and communicate

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and what it is you're hearing.

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I promise you, I promise
you that sticking through it

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with this course, you will
start to pick up more and more

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and more of this foreign language

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and it will start to make more

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and more sense to you is certainly my goal

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and something I know that you can achieve

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absolutely without question.

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So hang in there, know that
you're going to be able to do it

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and you're gonna do an
amazing job with it.

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I have no doubt about that.

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If you do have questions along the way,

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I am at your disposal,

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please feel free to post
the discussion board,

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email me directly if you prefer,

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talk to your fellow classmates
on the discussion board.

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We're gonna do it, we're
gonna do it together.

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I look forward to
speaking with each of you

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on the discussion board.

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Take care.