WEBVTT 1 00:00:00.983 --> 00:00:03.284 Welcome to Module 9. 2 00:00:03.284 --> 00:00:07.440 This module starts our discussion of effect modification 3 00:00:07.440 --> 00:00:11.370 which is also called interaction or moderation. 4 00:00:11.370 --> 00:00:13.264 You'll hear those terms used interchangeably 5 00:00:13.264 --> 00:00:17.677 throughout this module and in epidemiology in general. 6 00:00:17.677 --> 00:00:19.020 If we take a step back, 7 00:00:19.020 --> 00:00:22.560 we've been talking about threats to internal validity 8 00:00:22.560 --> 00:00:25.265 in EPI studies since Module 5. 9 00:00:25.265 --> 00:00:26.873 We started out with bias 10 00:00:26.873 --> 00:00:30.437 and then we spent three modules talking about confounding. 11 00:00:30.437 --> 00:00:32.490 We'll spend the next three modules 12 00:00:32.490 --> 00:00:36.431 talking about effect modification using the same structure. 13 00:00:36.431 --> 00:00:38.326 We'll start here in module 9, 14 00:00:38.326 --> 00:00:39.831 going over the theoretical 15 00:00:39.831 --> 00:00:43.261 and conceptual framework of effect modification. 16 00:00:43.261 --> 00:00:44.583 Then in the next module, 17 00:00:44.583 --> 00:00:47.761 we'll extend that information into SPSS 18 00:00:47.761 --> 00:00:49.444 and the statistical techniques 19 00:00:49.444 --> 00:00:53.110 behind controlling for effect modification. 20 00:00:53.110 --> 00:00:55.350 And then in Module 11, 21 00:00:55.350 --> 00:00:56.843 we'll look at interpreting the results 22 00:00:56.843 --> 00:01:00.857 of effect modification in the public health literature. 23 00:01:00.857 --> 00:01:04.621 Effect modification and confounding are similar in concept 24 00:01:04.621 --> 00:01:07.343 but they're actually very different in practice. 25 00:01:07.343 --> 00:01:08.957 I recommend that you go back 26 00:01:08.957 --> 00:01:10.689 and review your EPI1 notes 27 00:01:10.689 --> 00:01:12.291 just to make sure you feel solid 28 00:01:12.291 --> 00:01:15.155 about the basic difference between the two. 29 00:01:15.155 --> 00:01:16.311 I've included the chapter 30 00:01:16.311 --> 00:01:20.188 from your EPI1 Gordis text on interaction for reading 31 00:01:20.188 --> 00:01:22.680 before you get into your current textbook 32 00:01:22.680 --> 00:01:25.302 because I think it will reinforce that solid grounding 33 00:01:25.302 --> 00:01:29.337 before you dive deeper into the detail and analysis piece. 34 00:01:29.337 --> 00:01:31.262 As always, please reach out with questions, 35 00:01:31.262 --> 00:01:33.363 and I'll see you in the next module.