Hello and welcome to module six
of Genetics for Clinicians, which is part two
of Inheritance Family History and Pedigrees.
To this week, we will get a little more into the weeds
of details of family history and pedigree
and get exposed to some very important concepts
in inheritance, like reduced penetrance,
variable expressivity, and familial risk.
We will also find out
how to represent non-traditional families in pedigrees.
Yes, we can.
I have moved around some of Tamara Williams' lectures
to fit the new course organization,
so don't get thrown off by the numberings
or what comes next slides in the lectures.
Just focus on the content
and try to understand how it fits into this module
and connects to the previous modules.
I am adding a third short lecture
as I did last week to this module.
This week, the additional lecture is on drawing pedigrees
in the age of reproductive assistive technology
and modern families.
I hope you enjoy it.
There is some repetition this week in the lectures,
so feel free to fast forward
if you feel you've really already got a strong grip on it.
Otherwise, repetition is good.
As always, there is a reading assignment
in the Berry textbook and assignment to be turned in
for which you need to watch the third lecture, my lecture,
and a discussion board assignment
that requires some preparation as well.
And then finally, there's a quiz.
The discussion board requires you to go to a website
which was designed to help families
collect their health histories
and share them with their healthcare providers.
And so your assignment is actually to go in
and try it out, use it for a real or imagined family,
and then comment on your experience in the discussion board.
Finally, another sort of change from previous years
prior to this year, 2019,
module six was a review of modules one through five.
In the reorganized course,
I'm not allotting an entire module for review.
However, I am keeping the review material
from that module in the course as optional
in case you want to review one on your own.
So you will find in the course materials for this module,
elements marked optional.
Those are the review elements,
including a lecture by Tamara Williams
that reviews the highlights of modules one through five.
If I required that, that would be a lot of lecture
for this module, so I'm making it optional,
but if you feel like you need solidification
of the work that we've been doing,
I highly recommend going ahead with that exercise.
I've also kept in an optional discussion board
for module one through five review questions and answers,
and we'll keep an eye on that through the week,
and I hope your learners who are ahead
and understanding it all will also help you out
by answering those questions.
So welcome to module six,
Continuation of Inheritance, Family History and Pedigrees.
I hope you enjoy this new material
and we look forward to another wonderful learning week.
Thank you for learning.