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Hello and welcome to module six

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of Genetics for Clinicians,
which is part two

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of Inheritance Family
History and Pedigrees.

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To this week, we will get a
little more into the weeds

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of details of family history and pedigree

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and get exposed to some
very important concepts

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in inheritance, like reduced penetrance,

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variable expressivity, and familial risk.

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We will also find out

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how to represent non-traditional
families in pedigrees.

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Yes, we can.

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I have moved around some of
Tamara Williams' lectures

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to fit the new course organization,

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so don't get thrown off by the numberings

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or what comes next slides in the lectures.

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Just focus on the content

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and try to understand how
it fits into this module

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and connects to the previous modules.

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I am adding a third short lecture

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as I did last week to this module.

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This week, the additional
lecture is on drawing pedigrees

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in the age of reproductive
assistive technology

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and modern families.

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I hope you enjoy it.

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There is some repetition
this week in the lectures,

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so feel free to fast forward

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if you feel you've really
already got a strong grip on it.

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Otherwise, repetition is good.

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As always, there is a reading assignment

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in the Berry textbook and
assignment to be turned in

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for which you need to watch
the third lecture, my lecture,

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and a discussion board assignment

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that requires some preparation as well.

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And then finally, there's a quiz.

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The discussion board requires
you to go to a website

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which was designed to help families

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collect their health histories

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and share them with their
healthcare providers.

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And so your assignment
is actually to go in

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and try it out, use it for
a real or imagined family,

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and then comment on your
experience in the discussion board.

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Finally, another sort of
change from previous years

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prior to this year, 2019,

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module six was a review of
modules one through five.

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In the reorganized course,

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I'm not allotting an
entire module for review.

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However, I am keeping the review material

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from that module in the course as optional

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in case you want to
review one on your own.

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So you will find in the course
materials for this module,

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elements marked optional.

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Those are the review elements,

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including a lecture by Tamara Williams

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that reviews the highlights
of modules one through five.

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If I required that, that
would be a lot of lecture

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for this module, so
I'm making it optional,

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but if you feel like
you need solidification

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of the work that we've been doing,

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I highly recommend going
ahead with that exercise.

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I've also kept in an
optional discussion board

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for module one through five
review questions and answers,

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and we'll keep an eye on
that through the week,

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and I hope your learners who are ahead

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and understanding it all
will also help you out

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by answering those questions.

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So welcome to module six,

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Continuation of Inheritance,
Family History and Pedigrees.

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I hope you enjoy this new material

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and we look forward to another
wonderful learning week.

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Thank you for learning.