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Hello, and welcome to Module 6.

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In this module, we will
continue our discussion

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of threats to internal validity.

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We're going to start
talking about confounding,

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which is actually one of my favorite parts

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of EPI methods to think about.

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This is the first of three modules

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in which we'll discuss confounding,

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getting increasingly complex as we go.

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You might remember back to your discussion

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of confounding in EPI I,

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where you talked about
how we're able to control

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or adjust for confounding in
the analysis phase of a study.

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In EPI I, we talked about adjusting

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and controlling for confounding
in terms of stratification.

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However, there are more advanced methods

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involving linear regression

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that we'll talk about
starting in the next module.

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Make sure that you're
feeling really comfortable

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and solid with the
information in this module

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because we're going to keep building on it

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for the next few modules.

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So if you have questions
about what it means

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to be a confounder or some
of the basics of adjusting,

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please reach out to me or Itha

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before we move on to
regression in the next model.